Hepatic failure

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Hepatic failure
ICD-10 K72.9
DiseasesDB 5728
MeSH D017093

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms and keywords: Liver failure; fulminating hepatic failure

Overview

Liver failure is the inability of the liver to perform its normal synthetic and metabolic function as part of normal physiology.

Classification

Two forms are recognised:[1]

Causes

Drugs

Prognosis

The King's College criteria (KCC) may be used.

Contraindicated medications

Severe hepatic failure is considered an absolute contraindication to the use of the following medications:

The ALFSG index is a newer option that may be more accurate.[2]

References

  1. O'Grady JG, Schalm SW, Williams R. Acute liver failure: redefining the syndromes. Lancet 1993;342:273-5. PMID 8101303.
  2. Rutherford A, King LY, Hynan LS, Vedvyas C, Lin W, Lee WM; et al. (2012). "Development of an accurate index for predicting outcomes of patients with acute liver failure.". Gastroenterology. 143 (5): 1237–43. PMC 3480539Freely accessible. PMID 22885329. doi:10.1053/j.gastro.2012.07.113. 

See Also

cs:Jaterní selhánísv:Leversvikt

ur:فشل جگری



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