Levobetaxolol

Jump to: navigation, search
Levobetaxolol
File:Levobetaxolol-fill.png
File:Levobetaxolol.png
Clinical data
Pregnancy
category
  • US: C (Risk not ruled out)
Routes of
administration
topical (opthalmic)
Pharmacokinetic data
Elimination half-life20 hours
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC18H29NO3
Molar mass342.472 g/mol

Levobetaxolol or Levobetxolol hydrochloride is a drug used to lower the pressure in the eye in treating conditions such as glaucoma. It is typically marketed as a 0.5% opthalmic solution under the trade name Betaxon. Levobetaxolol is a beta-adrenergic receptor inhibitor (beta blocker.

Effect

Levobetaxolol inhibits the beta-1-adrenergic receptor. When applied topically, it reduces intra-ocular pressure (IOP) by 16-23% depending on time of day and the individual. It is indicated for IOP reduction in patients with open-angle glaucoma or ocular hypertension. Levobetaxolol has fewer cardiovascular side effects than other beta blockers.

Contraindications and side effects

Levobetaxolol should not be used by people who have sinus bradycardia, atrioventricular block, cardiogenic shock, or overt cardiac failure.

The drug has been associated with bradycardia and hypertension.



Linked-in.jpg