LCOR

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
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View/Edit Human

Ligand-dependent corepressor is a protein that in humans is encoded by the LCOR gene.[1][2][3]

Function

LCOR is a transcriptional corepressor widely expressed in fetal and adult tissues that is recruited to agonist-bound nuclear receptors through a single LxxLL motif, also referred to as a nuclear receptor (NR) box.[3]

References

  1. Fernandes I, Bastien Y, Wai T, Nygard K, Lin R, Cormier O, Lee HS, Eng F, Bertos NR, Pelletier N, Mader S, Han VK, Yang XJ, White JH (Jan 2003). "Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms". Mol Cell. 11 (1): 139–50. doi:10.1016/S1097-2765(03)00014-5. PMID 12535528.
  2. White JH, Fernandes I, Mader S, Yang XJ (Jun 2004). "Corepressor recruitment by agonist-bound nuclear receptors". Vitam Horm. 68: 123–43. doi:10.1016/S0083-6729(04)68004-6. PMID 15193453.
  3. 3.0 3.1 "Entrez Gene: LCOR ligand dependent nuclear receptor corepressor".

Further reading



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