Keratan sulfotransferase

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In enzymology, a keratan sulfotransferase (EC 2.8.2.21) is an enzyme that catalyzes the chemical reaction

3'-phosphoadenylyl sulfate + keratan adenosine 3',5'-bisphosphate + keratan 6'-sulfate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and keratan, whereas its two products are adenosine 3',5'-bisphosphate and keratan 6'-sulfate.

This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:keratan 6'-sulfotransferase. Other names in common use include 3'-phosphoadenylyl keratan sulfotransferase, keratan sulfate sulfotransferase, and 3'-phosphoadenylylsulfate:keratan sulfotransferase.

References

  • IUBMB entry for 2.8.2.21
  • BRENDA references for 2.8.2.21 (Recommended.)
  • PubMed references for 2.8.2.21
  • PubMed Central references for 2.8.2.21
  • Google Scholar references for 2.8.2.21
  • Ruter ER, Kresse H (1984). "Partial purification and characterization of 3'-phosphoadenylylsulfate:keratan sulfate sulfotransferases". J. Biol. Chem. 259: 11771&ndash, 6. PMID 6592165.

External links

The CAS registry number for this enzyme class is 62168-79-0.

Gene Ontology (GO) codes


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