Isopropyl alcohol

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Isopropyl alcohol
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

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NOTE: Most over the counter (OTC) are not reviewed and approved by the FDA. However, they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.

Overview

Isopropyl alcohol is an antiseptic that is FDA approved for the treatment of cuts, scrapes and minor muscular aches. Common adverse reactions include hypersensitivity.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

to decrease germs in minor cuts and scrapes. helps relieve minor muscular aches due to exertion.

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Isopropyl alcohol in adult patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Isopropyl alcohol in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

There is limited information regarding FDA-Labeled Use of Isopropyl alcohol in pediatric patients.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Isopropyl alcohol in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Isopropyl alcohol in pediatric patients.

Contraindications

There is limited information regarding Isopropyl alcohol Contraindications in the drug label.

Warnings

  • For external use only
  • Flammable, keep away from fire and flame will produce serious gastric disturbances if taken internally
  • Ask a doctor before use if you have deep puncture wounds or serious burns
  • When using this product do not get into eyes or mucous membranes use only in a well-ventilated area.
  • Stop use and ask a doctor if condition persists or gets worse.
  • Keep out of reach of children. In case of an accidental ingestion, contact a Poison Control Center immediately.

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Clinical Trial Experience of Isopropyl alcohol in the drug label.

Postmarketing Experience

There is limited information regarding Postmarketing Experience of Isopropyl alcohol in the drug label.

Drug Interactions

There is limited information regarding Isopropyl alcohol Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA):

  • Pregnancy Category


Pregnancy Category (AUS):

  • Australian Drug Evaluation Committee (ADEC) Pregnancy Category

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Isopropyl alcohol in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Isopropyl alcohol during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Isopropyl alcohol with respect to nursing mothers.

Pediatric Use

There is no FDA guidance on the use of Isopropyl alcohol with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of Isopropyl alcohol with respect to geriatric patients.

Gender

There is no FDA guidance on the use of Isopropyl alcohol with respect to specific gender populations.

Race

There is no FDA guidance on the use of Isopropyl alcohol with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Isopropyl alcohol in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Isopropyl alcohol in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Isopropyl alcohol in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Isopropyl alcohol in patients who are immunocompromised.

Administration and Monitoring

Administration

Monitoring

There is limited information regarding Monitoring of Isopropyl alcohol in the drug label.

IV Compatibility

There is limited information regarding IV Compatibility of Isopropyl alcohol in the drug label.

Overdosage

There is limited information regarding Isopropyl alcohol overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.

Pharmacology

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Isopropyl alcohol
IUPAC name isopropyl alcohol
Other names Propan-2-ol; Isopropanol; Rubbing alcohol; sec-Propyl alcohol; s-Propanol; iPrOH; IPA
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
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KEGG
RTECS number NT8050000
UNII
Properties
C3H8O
Molar mass 60.10 g·mol−1
Appearance Colorless liquid
Density 0.786 g/cm3 (20 °C)
Melting point
Boiling point
Solubility miscible in benzene, chloroform, ethanol, ether, glycerin
soluble in acetone
insoluble in salt solutions
Acidity (pKa) 16.5[1]
Refractive index (nD) 1.3776
Viscosity 2.86 cP at 15 °C
1.96 cP at 25 °C[2]
1.77 cP at 30 °C[2]
Dipole moment 1.66 D (gas)
Hazards
Main hazards Flammable
Flash point {{{value}}}
Explosive limits 2–12.7%
Related compounds
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Mechanism of Action

There is limited information regarding Isopropyl alcohol Mechanism of Action in the drug label.

Structure

There is limited information regarding Isopropyl alcohol Structure in the drug label.

Pharmacodynamics

There is limited information regarding Pharmacodynamics of Isopropyl alcohol in the drug label.

Pharmacokinetics

There is limited information regarding Pharmacokinetics of Isopropyl alcohol in the drug label.

Nonclinical Toxicology

There is limited information regarding Nonclinical Toxicology of Isopropyl alcohol in the drug label.

Clinical Studies

There is limited information regarding Clinical Studies of Isopropyl alcohol in the drug label.

How Supplied

There is limited information regarding Isopropyl alcohol How Supplied in the drug label.

Storage

There is limited information regarding Isopropyl alcohol Storage in the drug label.

Images

Drug Images

Package and Label Display Panel

IPL 01.jpg
This image of the FDA label is provided by the National Library of Medicine.
DailyMed - ISOPROPYL RUBBING ALCOHOL - isopropyl alcohol liquid .png
This image of the FDA label is provided by the National Library of Medicine.

Patient Counseling Information

  • Apply to skin directly or with clean gauze, cotton or swab.
  • For rubbing, apply liberally and rub with hands.

Precautions with Alcohol

  • Alcohol-Isopropyl alcohol interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

  • ISOPROPYL RUBBING ALCOHOL®[4]

Look-Alike Drug Names

There is limited information regarding Isopropyl alcohol Look-Alike Drug Names in the drug label.

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

  1. Reeve, W.; Erikson, C.M.; Aluotto, P.F. (1979). "A new method for the determination of the relative acidities of alcohols in alcoholic solutions. The nucleophilicities and competitive reactivities of alkoxides and phenoxides". Can. J. Chem. 57 (20): 2747. doi:10.1139/v79-444.
  2. 2.0 2.1 Yaws, C.L. (1999). Chemical Properties Handbook. McGraw-Hill. ISBN 0-07-073401-1.
  3. NIOSH Pocket Guide to Chemical Hazards 0359
  4. "ISOPROPYL RUBBING ALCOHOL - isopropyl alcohol liquid".

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