Interleukin-15 receptor

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interleukin 15 receptor, alpha
File:Protein IL15RA PDB 2ers.png
Identifiers
SymbolIL15RA
Entrez3601
HUGO5978
OMIM601070
RefSeqNM_172200
UniProtQ13261
Other data
LocusChr. 10 p15-10p14
interleukin 2 receptor, beta
File:Protein IL2RB PDB 2b5i.png
Identifiers
SymbolIL2RB
Alt. symbolsCD122
Entrez3560
HUGO6009
OMIM146710
RefSeqNM_000878
UniProtP14784
Other data
LocusChr. 22 q13
interleukin 2 receptor, gamma (severe combined immunodeficiency)
File:Protein IL2RG PDB 2b5i.png
Identifiers
SymbolIL2RG
Alt. symbolsSCIDX1, IMD4
Entrez3561
HUGO6010
OMIM308380
RefSeqNM_000206
Other data
LocusChr. X q13

Interleukin-15 receptor is a type I cytokine receptor, binding interleukin-15. It consists of an interleukin 15 receptor, alpha subunit and shares common beta and gamma subunits with the IL-2 receptor.[1]

References

  1. Anderson DM, Kumaki S, Ahdieh M, Bertles J, Tometsko M, Loomis A, Giri J, Copeland NG, Gilbert DJ, Jenkins NA (1995). "Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes". J. Biol. Chem. 270 (50): 29862–9. doi:10.1074/jbc.270.50.29862. PMID 8530383.

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