Insulinoma epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amandeep Singh M.D.[2]

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Overview

The incidence of insulinoma is approximately 0.1-0.4 per 100,000 individuals that constitute 1-2% of all pancreatic neoplasms. The female to male ratio is approximately 3:2. There is no regional predisposition.

Epidemiology and Demographics

Incidence

Age

  • Patients of all age groups may develop insulinoma.
  • Insulinoma commonly affects individuals 40-60 years of age.

Race

  • There is no racial predilection to insulinoma.

Gender

  • Females (60-75%) are more commonly affected by insulinoma than males. The female to male ratio is approximately 3:2.[2]

Region

  • There is no regional predisposition but it was described according to local studies. One of the best studies ever conducted for insulinoma, by Mayo clinic, showed the incidence of insulinoma in residents of Olmsted County, Minnesota over the time frame of 60 years.

References

  1. Okabayashi T, Shima Y, Sumiyoshi T, Kozuki A, Ito S, Ogawa Y, Kobayashi M, Hanazaki K (2013). "Diagnosis and management of insulinoma". World J. Gastroenterol. 19 (6): 829–37. doi:10.3748/wjg.v19.i6.829. PMC 3574879. PMID 23430217.
  2. 2.0 2.1 Service FJ, McMahon MM, O'Brien PC, Ballard DJ (1991). "Functioning insulinoma--incidence, recurrence, and long-term survival of patients: a 60-year study". Mayo Clin. Proc. 66 (7): 711–9. PMID 1677058.

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