ITGA10

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Integrin alpha-10 also known as ITGA10 is a protein that in humans is encoded by the ITGA10 gene.[1][2][3]

Function

Integrins are integral membrane proteins composed of an alpha chain and a beta chain, and are known to participate in cell adhesion as well as cell-surface mediated signalling. The I-domain containing alpha 10 combines with the integrin beta 1 chain (ITGB1) to form a novel collagen type II-binding integrin expressed in cartilage tissue.[1]

Related gene problems

References

  1. 1.0 1.1 "Entrez Gene: ITGA10 integrin, alpha 10".
  2. Camper L, Hellman U, Lundgren-Akerlund E (August 1998). "Isolation, cloning, and sequence analysis of the integrin subunit alpha10, a beta1-associated collagen binding integrin expressed on chondrocytes". J. Biol. Chem. 273 (32): 20383–9. doi:10.1074/jbc.273.32.20383. PMID 9685391.
  3. Lehnert K, Ni J, Leung E, Gough S, Morris CM, Liu D, Wang SX, Langley R, Krissansen GW (1999). "The integrin alpha10 subunit: expression pattern, partial gene structure, and chromosomal localization". Cytogenet. Cell Genet. 87 (3–4): 238–44. doi:10.1159/000015434. PMID 10702680.
  4. Klopocki E, Schulze H, Strauss G, et al. (February 2007). "Complex Inheritance Pattern Resembling Autosomal Recessive Inheritance Involving a Microdeletion in Thrombocytopenia–Absent Radius Syndrome". Am. J. Hum. Genet. 80 (2): 232–40. doi:10.1086/510919. PMC 1785342. PMID 17236129.

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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