Hypoxanthine

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Template:Chembox E number
Hypoxanthine
IUPAC name 3,7-dihydropurin-6-one
Identifiers
3D model (JSmol)
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MeSH Hypoxanthine
Properties
C5H4N4O
Molar mass 136.112
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Hypoxanthine is a naturally occurring purine derivative.

It is occasionally found as a constituent of nucleic acids where it is present in the anticodon of tRNA in the form of its nucleoside inosine.

Reactions

It is one of the products of the action of xanthine oxidase on xanthine, though more normally in purine degradation, hypoxanthine is formed from oxidation of xanthine by xanthine oxidase.

Hypoxanthine-guanine phosphoribosyltransferase converts hypoxanthine into IMP in nucleotide salvage.

Hypoxanthine is also a spontaneous deamination product of adenine. Because of its resemblance to guanine, the spontaneous deamination of adenine can lead to an error in DNA transcription/replication.

Additional images

External links

de:Hypoxanthin


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