Hypoglycemia causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Carlos A Lopez, M.D. [2] Mohammed Abdelwahed M.D[3]

Overview

Causes of hypoglycemia depend on age; neonatal causes are transient neonatal hypoglycemia, Prematurity, intrauterine growth retardation, perinatal asphyxia, sepsis, congenital hypopituitarism, beta sympathomimetic drugs, congenital hyperinsulinism, infant of a diabetic mother, Beckwith-Wiedemann syndrome and inborn errors of carbohydrate metabolism. Causes of adult hypoglycemia are: insulin or insulin secretagogue drugs, alcohol, hepatic failure, renal failure, cardiac failure, sepsis, non-islet cell pancreatic tumors, insulinoma, reactive hypoglycemia, post gastric bypass hypoglycemia, and autoimmunee hypoglycemia.

Causes of hypoglycemia

Hypoglycemia in Newborn Infants

Hypoglycemia in Adults

References

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  2. Stanley CA, Baker L (1999). "The causes of neonatal hypoglycemia.". N Engl J Med. 340 (15): 1200–1. PMID 10202173. doi:10.1056/NEJM199904153401510. 
  3. Bateman BT, Patorno E, Desai RJ, Seely EW, Mogun H, Maeda A; et al. (2016). "Late Pregnancy β Blocker Exposure and Risks of Neonatal Hypoglycemia and Bradycardia.". Pediatrics. 138 (3). PMC 5005024Freely accessible. PMID 27577580. doi:10.1542/peds.2016-0731. 
  4. Buraczewska B, Kopacz K, Myśliwiec M (2013). "Hyperinsulinism as a common cause of hypoglycemia in children - pathogenesis, diagnosis and treatment.". Pediatr Endocrinol Diabetes Metab. 19 (1): 24–8. PMID 23739646. 
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  6. Sue CM, Hirano M, DiMauro S, De Vivo DC (1999). "Neonatal presentations of mitochondrial metabolic disorders.". Semin Perinatol. 23 (2): 113–24. PMID 10331464. 
  7. Burton BK (1998). "Inborn errors of metabolism in infancy: a guide to diagnosis.". Pediatrics. 102 (6): E69. PMID 9832597. 
  8. Worthen HG, al Ashwal A, Ozand PT, Garawi S, Rahbeeni Z, al Odaib A; et al. (1994). "Comparative frequency and severity of hypoglycemia in selected organic acidemias, branched chain amino acidemia, and disorders of fructose metabolism.". Brain Dev. 16 Suppl: 81–5. PMID 7726385. 
  9. Cryer PE, Axelrod L, Grossman AB, Heller SR, Montori VM, Seaquist ER; et al. (2009). "Evaluation and management of adult hypoglycemic disorders: an Endocrine Society Clinical Practice Guideline.". J Clin Endocrinol Metab. 94 (3): 709–28. PMID 19088155. doi:10.1210/jc.2008-1410. 
  10. Szoke E, Gosmanov NR, Sinkin JC, Nihalani A, Fender AB, Cryer PE; et al. (2006). "Effects of glimepiride and glyburide on glucose counterregulation and recovery from hypoglycemia.". Metabolism. 55 (1): 78–83. PMID 16324923. doi:10.1016/j.metabol.2005.07.009. 
  11. Parekh TM, Raji M, Lin YL, Tan A, Kuo YF, Goodwin JS (2014). "Hypoglycemia after antimicrobial drug prescription for older patients using sulfonylureas.". JAMA Intern Med. 174 (10): 1605–12. PMC 4878670Freely accessible. PMID 25179404. doi:10.1001/jamainternmed.2014.3293.  Review in: Ann Intern Med. 2015 Feb 17;162(4):JC13
  12. Maitra SR, Wojnar MM, Lang CH (2000). "Alterations in tissue glucose uptake during the hyperglycemic and hypoglycemic phases of sepsis.". Shock. 13 (5): 379–85. PMID 10807013. 
  13. Odenwald B, Nennstiel-Ratzel U, Dörr HG, Schmidt H, Wildner M, Bonfig W (2016). "Children with classic congenital adrenal hyperplasia experience salt loss and hypoglycemia: evaluation of adrenal crises during the first 6 years of life.". Eur J Endocrinol. 174 (2): 177–86. PMID 26563979. doi:10.1530/EJE-15-0775. 
  14. Galati SJ, Rayfield EJ (2014). "Approach to the patient with postprandial hypoglycemia.". Endocr Pract. 20 (4): 331–40. PMID 24246338. doi:10.4158/EP13132.RA. 
  15. Lupsa BC, Chong AY, Cochran EK, Soos MA, Semple RK, Gorden P (2009). "Autoimmune forms of hypoglycemia.". Medicine (Baltimore). 88 (3): 141–53. PMID 19440117. doi:10.1097/MD.0b013e3181a5b42e. 

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