Hydroxypethidine

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Hydroxypethidine
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Clinical data
SynonymsHydroxypethidine, Bemidone
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC15H21NO3
Molar mass263.332 g/mol

Hydroxypethidine (Bemidone) is an opioid analgesic that is an analogue of pethidine (meperidine). Hydroxypethidine is significantly less potent than meperidine as an analgesic, (0.3x meperidine in potency) although it also has NMDA antagonist properties like its close relative ketobemidone. [1]

Hydroxypethidine has similar effects to other opioids, and produces analgesia, sedation and euphoria. Side effects can include itching, nausea and potentially serious respiratory depression which can be life-threatening.

References

  1. Isbell Harris. The addiction liability of some analogues of meperidine. Journal of Pharmacology And Experimental Therapeutics, 1949; 97(2): 182-190

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