Homovanillic acid

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Template:Chembox E number
Homovanillic acid
IUPAC name 2-(4-Hydroxy-3-methoxy-phenyl)acetic acid
Identifiers
3D model (JSmol)
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MeSH Homovanillic+acid
Properties
C9H10O4
Molar mass 182.173
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Homovanillic acid (HOC6H3(OCH3)CH2COOH; synonyms: 3-Methoxy-4-hydroxyphenyl acetic acid; HVA; 4-Hydroxy-3-methoxy-benzeneacetic acid; 4-Hydroxy-3-methoxyphenylacetic acid) is a major catecholamine metabolite. It is used as a reagent to detect oxidative enzymes.

In psychiatry and neuroscience, brain and cerebrospinal fluid levels of HVA are measured as a marker of metabolic stress caused by 2-deoxy-D-glucose.[1]

References

  1. Marcelis M, Suckling J, Hofman P, Woodruff P, Bullmore E, van Os J (2006). "Evidence that brain tissue volumes are associated with HVA reactivity to metabolic stress in schizophrenia". Schizophr. Res. 86 (1–3): 45–53. doi:10.1016/j.schres.2006.05.001. PMID 16806836. Unknown parameter |month= ignored (help)

Template:Aromatic-stub Template:Neurotransmitter metabolism intermediates


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