HLA-B67

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major histocompatibility complex (human), class I, B67
Alleles B*6701 </br>
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*6701
Locus chr.6 6p21.31

HLA-B67 (B67) is an HLA-B serotype. The serotype identifies the more common HLA-B*67 gene products.[1] B67 is region specific recombinant haplotype formed by the gene conversion of B*39, an allele common along the Northwest Pacific Rim (Taiwan, Japan, Korea, Coastal Siberia), and B7, B22, or B27.[2] (For terminology help see: HLA-serotype tutorial)

Serotype

B67 Serotype recognition of the B*67 allele-group gene products[3]
B*67 B67 Other Sample
allele  %  % size (N)
6701 32 62 81


By allele

Regions of higher B*6701 frequency
Japan LocationMapJapan.png
Taiwan LocationTaiwan.png
Heilongjiang
province, China
(Harbin city)
China-Heilongjiang.png
Beijing
China
China-Beijing.png
Shandong
peninsula
Location-of-Shandong-Peninsula.png
HLA B*6701 frequencies
freq
ref. Population (%)
[4] Osaka Region (Japan) 2.6
[4] Hakka (Taiwan) 1.8
[4] Japan (5) 1.7
[4] Harbin Man (China) 1.7
[4] Beijing (China) 1.5
[4] Linqu (Shandong, China) 1.1
[4] Siraya (Taiwan) 1.0
[4] Portugal South 1.0
[4] Oold (Mongolia) 1.0
[4] American Samoa 1.0
[4] Pazeh (Taiwan) 0.9
[4] South Korea (3) 0.9
[4] N. Korean (Harbin,China) 0.8
[4] Arratia Basque (Spain) 0.6
[4] Tarialan Khoton (Mongolia) 0.6
[4] Shanghai (China) 0.6
[4] Natal Zulu (South African) 0.5
[4] Yunnan Han (China) 0.5
[4] Turkey 0.4
[4] Southern Han (China) 0.4
[4] Tuva (Russia) 0.3
[4] Chinese (Hong Kong , China) 0.1

References

  1. Marsh SG, Albert ED, Bodmer WF; et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens. 65 (4): 301–69. PMID 15787720. doi:10.1111/j.1399-0039.2005.00379.x. 
  2. Little AM, Domena JD, Hildebrand WH; et al. (1994). "HLA-B67: a member of the HLA-B16 family that expresses the ME1 epitope". Tissue Antigens. 43 (1): 38–43. PMID 7517584. 
  3. derived from IMGT/HLA
  4. 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 4.12 4.13 4.14 4.15 4.16 4.17 4.18 4.19 4.20 4.21 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. PMID 12753660.  External link in |title= (help)

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