HLA-B42

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major histocompatibility complex (human), class I, B42
Alleles B*4201 </br> B*4202 </br>
Structure (See HLA-B)
Symbol(s) HLA-B
EBI-HLA B*4201
EBI-HLA B*4202
Locus chr.6 6p21.31

HLA-B42 (B42) is an HLA-B serotype. The serotype identifies the HLA-B*4201 and *4202 gene products.[1] HLA-B*4201 is common Central Africa. (For terminology help see: HLA-serotype tutorial)

Serotype

B42 serotype recognition of Some HLA B*42 allele-group gene products[2]
B*42 B42 other Sample
allele  %  % size (N)
4201 93 2 1015
4202 95 80

Serological typing for B*4201 and B*4202 is relatively efficient.


B*4201 allele frequencies

HLA B*4201 frequencies
freq
ref. Population (%)
[3] Zambia Lusaka 14.8
[3] Mali Bandiagara 13.8
[3] Burkina Faso Mossi 13.2
[3] South Africian Natal Zulu 12.0
[3] Burkina Faso Rimaibe 9.6
[3] South Africa Tswana 8.5
[3] Kenya Luo 7.7
[3] Kenya 7.3
[3] Kenya Nandi 6.9
[3] Zimbabwe Harare Shona 6.9
[3] Saudi Arabia 5.6
[3] Cameroon Yaounde 4.9
[3] Cameroon Beti 4.0
[3] Cameroon Bamileke 3.9
[3] Cameroon Sawa 3.8
[3] Ivory Coast Akan Adiopodoume 3.4
[3] Israel Gaza Palestinians 2.4
[3] India North Delhi 2.2
[3] Senegal Niokholo Mandenka 1.6
[3] Mbenzele Pygmy (C. Afr. Rep.) 1.5
[3] Iran Baloch 1.5
[3] Pakistan Baloch 1.5
[3] Sudanese 1.5
[3] Tunisia 1.5
[3] Pakistan Brahui 1.4
[3] Cameroon Bamileke 1.3
[3] Oman 1.3
[3] Sudanese 1.3
[3] Tunisia Tunis 1.1
[3] Zimbabwe Harare Shona 1.1
[3] Cameroon Bakola Pygmy 1.0
[3] Pakistan Pathan 1.0
[3] Portugal Centre 1.0
[3] Saudi Arabia Guraiat and Hail 1.0
[3] Morocco Casablanca 0.9
[3] Senegal Dakar 0.9
[3] Uganda Kampala 0.9
[3] Cape Verde Southeastern Islands 0.8
[3] Guinea Bissau 0.8
[3] United Arab Emerates 0.8
[3] Morocco Nador Metalsa Class I 0.7
[3] Pakistan Karachi Parsi 0.6
[3] Spain Majorca 0.6
[3] China Yunnan Han pop2 0.5
[3] England Newcastle 0.5
[3] Israel Arab Druse 0.5
[3] Israel Jews 0.5
[3] Italy Rome 0.5
[3] Guadalajara Mestizos (2) (Mexico) 0.5
[3] Morocco 0.5
[3] Pakistan Sindhi 0.5
[3] Senegal Niokholo Mandenka 0.5
[3] Singapore Riau Malay 0.5

References

  1. Marsh SG, Albert ED, Bodmer WF; et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens. 65 (4): 301–69. PMID 15787720. doi:10.1111/j.1399-0039.2005.00379.x. 
  2. derived from IMGT/HLA
  3. 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 3.14 3.15 3.16 3.17 3.18 3.19 3.20 3.21 3.22 3.23 3.24 3.25 3.26 3.27 3.28 3.29 3.30 3.31 3.32 3.33 3.34 3.35 3.36 3.37 3.38 3.39 3.40 3.41 3.42 3.43 3.44 3.45 3.46 3.47 3.48 3.49 3.50 3.51 3.52 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. PMID 12753660.  External link in |title= (help)

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