HLA-A43

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major histocompatibility complex (human), class I, A43
Alleles A*4301
Structure (See HLA-A)
Symbol(s) HLA-A
EBI-HLA A*4301
Locus chr.6 6p21.31

HLA-A43 (A43) is an HLA-A serotype. The serotype identifies the more common HLA-A*43 gene products. A43 is a split antigen type of the A10 broad antigen type. A*4301 is believed to have been formed by a single gene conversion between another HLA-A and the A*2601 allele.[1] A43 is more common in Africa. A*4301 is rare.

Serotype

A26 serotype recognition of Some HLA A*4301 allele gene products[2]
A*43 --- A26 Sample
allele  %  % size (N)
4301 35 9


A43 frequencies

HLA A*4301 frequencies
freq
ref. Population (%)
[3] South Africa Tswana 4.9
[3] South Africian Natal Zulu 3.0
[3] China Yunnan Han 1.2
[3] Zambia Lusaka 1.2
[3] Pakistan Karachi Parsi 0.6
[3] India North Delhi 0.5
[3] Zimbabwe Harare Shona 0.4
[3] Italy 0.01
[3] China Shanghai 0.002

References

  1. Madrigal JA, Hildebrand WH, Belich MP; et al. (1993). "Structural diversity in the HLA-A10 family of alleles: correlations with serology". Tissue Antigens. 41 (2): 72–80. PMID 8475492. 
  2. derived from IMGT/HLA
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 3.8 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. PMID 12753660.  External link in |title= (help)



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