H₂ receptor

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histamine receptor H2
Identifiers
SymbolHRH2
Entrez3274
HUGO5183
OMIM142703
RefSeqNM_022304
UniProtP25021
Other data
LocusChr. 5 q35

H2 receptors positively coupled to adenylate cyclase via Gs. It is a potent stimulant of cAMP production. It increases the intracellular Ca2+ concentrations and release Ca2+ from intracellular stores.

The drug Betazole is an example of a Histamine H2 receptor agonist.

Location

Response

H2-receptor agonists and antagonists

see H2-receptor agonist and H2-receptor antagonist

External links


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