Guanosine diphosphate

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Guanosine diphosphate
Chemical name Guanosine 5'-(trihydrogen diphosphate)
Chemical formula C10H15N5O11P2
Molecular mass 443.20 g/mol
CAS number 146-91-8
SMILES O[C@H]1[C@H]([C@H](N2C(N=
C(N)NC3=O)=C3N=C2)O[C@@H]
1COP(O)(OP(O)(O)=O)=O)O
Chemical structure of deprotonated GDP

Guanosine diphosphate, abbreviated GDP, is a nucleotide. It is an ester of pyrophosphoric acid with the nucleoside guanosine. GDP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase guanine.

GDP is the product of GTP dephosphorylation by GTPases, e.g. the G-proteins that are involved in signal transduction.

Biologicaly GDP is converted into GTP with the help of pyruvate kinase and phosphoenolpyruvate

See also

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Major families of biochemicals
Peptides | Amino acids | Nucleic acids | Carbohydrates | Nucleotide sugars | Lipids | Terpenes | Carotenoids | Tetrapyrroles | Enzyme cofactors | Steroids | Flavonoids | Alkaloids | Polyketides | Glycosides
Analogues of nucleic acids:Types of Nucleic AcidsAnalogues of nucleic acids:
Nucleobases: Purine (Adenine, Guanine) | Pyrimidine (Uracil, Thymine, Cytosine)
Nucleosides: Adenosine/Deoxyadenosine | Guanosine/Deoxyguanosine | Uridine | Thymidine | Cytidine/Deoxycytidine
Nucleotides: monophosphates (AMP, GMP, UMP, CMP) | diphosphates (ADP, GDP, UDP, CDP) | triphosphates (ATP, GTP, UTP, CTP) | cyclic (cAMP, cGMP, cADPR)
Deoxynucleotides: monophosphates (dAMP, dGMP, TMP, dCMP) | diphosphates (dADP, dGDP, TDP, dCDP) | triphosphates (dATP, dGTP, TTP, dCTP)
Ribonucleic acids: RNA | mRNA | tRNA | rRNA | gRNA | miRNA | ncRNA | piRNA | shRNA | siRNA | snRNA | snoRNA
Deoxyribonucleic acids: DNA | mtDNA | cDNA
Nucleic acid analogues: GNA | LNA | PNA | TNA | morpholino
Cloning vectors: plasmid | cosmid | fosmid | phagemid | BAC | YAC | HAC


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