Granulosa cell tumour surgery

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Surgery is the mainstay of treatment for granulosa cell tumor.[1][2] Unilateral salpingo-oophorectomy (fertility preserving surgery) is indicated among young patients, who have future pregnancy plans, and present with a stage I granulosa cell tumor.

Surgery

  • Surgery is the mainstay of treatment for granulosa cell tumor.[1][2]
  • The intial management of granulosa cell tumor patients is surgical staging.
  • Surgical staging of granulosa cell tumor is achieved through:
  • A vertical midline incision
  • Exploration of peritoneal cavity
  • Peritoneal wash for cytology
  • Peritoneal biopsies from multiple sites of the abdomen and peritoneal cavity
  • Nodal biopsies (inguinal and retro-peritoneal lymph nodes)
  • Omentectomy
  • The feasibility of surgery depends on:
  • The patients future pregnancy plans
  • The stage of granulosa cell tumor at the time of diagnosis
  • Total abdominal hysterectomy and bilateral salpingo-oophorectomy is indicated among patients with no future pregnancy plans.
  • Unilateral salpingo-oophorectomy (fertility preserving surgery) is indicated among young patients, who have future pregnancy plans, and present with a stage I granulosa cell tumor.

References

  1. 1.0 1.1 Kottarathil VD, Antony MA, Nair IR, Pavithran K (2013). "Recent advances in granulosa cell tumor ovary: a review.". Indian J Surg Oncol. 4 (1): 37–47. PMC 3578540Freely accessible. PMID 24426698. doi:10.1007/s13193-012-0201-z. 
  2. 2.0 2.1 Pectasides D, Pectasides E, Psyrri A (2008). "Granulosa cell tumor of the ovary.". Cancer Treat Rev. 34 (1): 1–12. PMID 17945423. doi:10.1016/j.ctrv.2007.08.007. 

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