Activation and inactivation
Arrangement of subunits
Strychnine-sensitive glycine receptors are members of a family of Ligand-gated ion channels. Receptors of this family are arranged as five subunits surrounding a central pore, with each subunit composed of four α helical transmembrane segments.
The adult form of the GlyR is the heteromeric α1β receptor, which is believed to have a stoichiometry (proportion) of three α1 subunits and two β subunits  or four α1 subunits and one β subunit. The α-subunits are also able to form functional homo-pentameric receptors in heterologous expression systems in African clawed frog's oocytes or mammalian cell lines, and the α1 homomeric receptor is essential for studies of channel pharmacokinetics and pharmacodynamics.
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- Miyazawa, A (2003). "Structure and gating mechanism of the acetylcholine receptor pore". Nature. 423 (6943): 949–955. PMID 12827192. Unknown parameter
- Kuhse, J (1993). "Assembly of the inhibitory glycine receptor: identification of amino acid sequence motifs governing subunit stoichiometry". Neuron. 11 (6): 1049–1056. PMID 8274276. Unknown parameter
- Kuhse, J (1995). "The inhibitory glycine receptor: architecture, synaptic localization and molecular pathology of a postsynaptic ion-channel complex". Current Opinion in Neurobiology. 5 (3): 318–323. PMID 7580154. Unknown parameter
- Lewis, TM (2003). "Kinetic determinants of agonist action at the recombinant human glycine receptor". Journal of Physiology. 549 (Part 2): 361–374. PMID 12679369. Retrieved 2007-01-16. Unknown parameter
- "OMIM - STIFF-PERSON SYNDROME; SPS". Retrieved 2007-06-20.