Glycine N-acyltransferase

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In enzymology, a glycine N-acyltransferase (EC is an enzyme that catalyzes the chemical reaction

acyl-CoA + glycine CoA + N-acylglycine

Thus, the two substrates of this enzyme are acyl-CoA and glycine, whereas its two products are CoA and N-acylglycine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:glycine N-acyltransferase. Other names in common use include glycine acyltransferase, and glycine-N-acylase.


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  • Nandi DL, Lucas SV, Webster LT Jr (1979). "Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization". J. Biol. Chem. 254: 7230&ndash, 7. PMID 457678.
  • SCHACHTER D, TAGGART JV (1954). "Glycine N-acylase: purification and properties". J. Biol. Chem. 208: 263&ndash, 75. PMID 13174534.
  • Webster LT, Siddiqui UA, Lucas SV, Strong JM, Mieyal JJ (1976). "Identification of separate acyl- CoA:glycine and acyl-CoA:L-glutamine N-acyltransferase activities in mitochondrial fractions from liver of rhesus monkey and man". J. Biol. Chem. 251: 3352&ndash, 8. PMID 931988.

External links

The CAS registry number for this enzyme class is 9029-95-2.

Gene Ontology (GO) codes