Glucuronokinase

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In enzymology, a glucuronokinase (EC 2.7.1.43) is an enzyme that catalyzes the chemical reaction

ATP + D-glucuronate ADP + 1-phospho-alpha-D-glucuronate

Thus, the two substrates of this enzyme are ATP and D-glucuronate, whereas its two products are ADP and 1-phospho-alpha-D-glucuronate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-glucuronate 1-phosphotransferase. Other names in common use include glucuronokinase (phosphorylating), and glucurono-glucuronokinase. This enzyme participates in pentose and glucuronate interconversions and ascorbate and aldarate metabolism.

References

  • IUBMB entry for 2.7.1.43
  • BRENDA references for 2.7.1.43 (Recommended.)
  • PubMed references for 2.7.1.43
  • PubMed Central references for 2.7.1.43
  • Google Scholar references for 2.7.1.43
  • Neufeld EF, Feingold DS and Hassid WZ (1959). "Enzymic phosphorylation of D-glucuronic acid by extracts from seedlings of Phaseolus aureus". Arch. Biochem. Biophys. 83: 96&ndash, 100.

External links

The CAS registry number for this enzyme class is 9026-62-4.

Gene Ontology (GO) codes


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