Fyn-related kinase

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
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RefSeq (mRNA)

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RefSeq (protein)

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Fyn-related kinase (FRK, formerly tyrosine protein kinase 5) is an enzyme that in humans is encoded by the FRK gene.[1][2]

The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth.[2]

Interactions

FRK has been shown to interact with retinoblastoma protein.[3]

References

  1. Lee J, Wang Z, Luoh SM, Wood WI, Scadden DT (April 1994). "Cloning of FRK, a novel human intracellular SRC-like tyrosine kinase-encoding gene". Gene. 138 (1–2): 247–51. doi:10.1016/0378-1119(94)90817-6. PMID 7510261.
  2. 2.0 2.1 "Entrez Gene: FRK fyn-related kinase".
  3. Craven, R J; Cance W G; Liu E T (September 1995). "The nuclear tyrosine kinase Rak associates with the retinoblastoma protein pRb". Cancer Res. UNITED STATES. 55 (18): 3969–72. ISSN 0008-5472. PMID 7664264.

Further reading



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