|Other names||β-D-fructose 6-phosphate, |
|Molar mass||262.1535 g/mol|
|Except where noted otherwise, data are given for|
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references
Fructose 6-phosphate (also known as the Neuberg ester) is fructose sugar phosphorylated on carbon 6 (ie. is a fructosephosphate). The β-D-form of this compound is very common in cells, the vast majority of glucose and fructose entering a cell will become converted to this at some point. The name Neuberg ester comes from the German biochemist Carl Neuberg.
Fructose 6-phosphate in glycolysis
|α-D-glucose 6-phosphate||Phosphoglucose isomerase||β-D-fructose 6-phosphate||Phosphofructokinase-1||β-D-fructose 1,6-bisphosphate|
|Phosphoglucose isomerase||Fructose bisphosphatase|
Fructose 6-phosphate isomerism
Fructose 6-phosphate has only one biologically active isomer, the β-D-form. There are many other isomers, analogous to those of fructose.
- Phosphofructokinase 2 is Fructose 2,6-bisphosphate. This is one of the regulatory reactions of glycolysis.
- Mannose phosphate isomerase creates mannose-6-phosphate.
NADH + H+
NADH + H+
Reversible left-right reaction arrow with minor forward product(s) to top right and minor reverse substrate(s) from bottom right
- Fruton, Joseph S. Proteins, Enzymes, Genes: The Interplay of Chemistry and Biology. Yale University Press: New Haven, 1999. p 292