Fatty acid-binding protein

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The fatty-acid-binding proteins (FABPs) are a family of carrier proteins for fatty acids and other lipophilic substances such as eicosanoids and retinoids.[1] These proteins are thought to facilitate the transfer of fatty acids between extra- and intracellular membranes.[2] Some family members are also believed to transport lipophilic molecules from outer cell membrane to certain intracellular receptors such as PPAR.[3]

Family members

Members of this family inlcude:

References

  1. Chmurzyńska A (2006). "The multigene family of fatty acid-binding proteins (FABPs): function, structure and polymorphism". J. Appl. Genet. 47 (1): 39–48. PMID 16424607.
  2. Weisiger RA (2002). "Cytosolic fatty acid binding proteins catalyze two distinct steps in intracellular transport of their ligands". Mol. Cell. Biochem. 239 (1–2): 35–43. doi:10.1023/A:1020550405578. PMID 12479566.
  3. Tan NS, Shaw NS, Vinckenbosch N, Liu P, Yasmin R, Desvergne B, Wahli W, Noy N (2002). "Selective cooperation between fatty acid binding proteins and peroxisome proliferator-activated receptors in regulating transcription". Mol. Cell. Biol. 22 (14): 5114–27. doi:10.1128/MCB.22.14.5114-5127.2002. PMID 12077340.

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