Fas-activated serine/threonine kinase
- ATP + [Fas-activated serine/threonine protein] ADP + [Fas-activated serine/threonine phosphoprotein]
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups protein-serine/threonine kinases. The systematic name of this enzyme class is ATP:[Fas-activated serine/threonine protein] phosphotransferase. Other names in common use include FAST, FASTK, and STK10.
- IUBMB entry for 220.127.116.11
- BRENDA references for 18.104.22.168 (Recommended.)
- PubMed references for 22.214.171.124
- PubMed Central references for 126.96.36.199
- Google Scholar references for 188.8.131.52
- Tian Q, Taupin J, Elledge S, Robertson M, Anderson P (1995). "Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis". J. Exp. Med. 182: 865&ndash, 74. PMID 7544399.
- Li W, Simarro M, Kedersha N, Anderson P (2004). "FAST is a survival protein that senses mitochondrial stress and modulates TIA-1-regulated changes in protein expression". Mol. Cell. Biol. 24: 10718&ndash, 32. PMID 15572676.
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