Dysplastic nevus historical perspective

Jump to: navigation, search

Dysplastic nevus Microchapters


Patient Information


Historical Perspective




Differentiating Dysplastic nevus from other Diseases

Epidemiology and Demographics

Risk Factors


Natural History, Complications and Prognosis


History and Symptoms

Physical Examination

Laboratory Findings

Other Imaging Findings

Other Diagnostic Studies


Medical Therapy


Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Dysplastic nevus historical perspective On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides


American Roentgen Ray Society Images of Dysplastic nevus historical perspective

All Images
Echo & Ultrasound
CT Images

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Dysplastic nevus historical perspective

CDC on Dysplastic nevus historical perspective

Dysplastic nevus historical perspective in the news

Blogs on Dysplastic nevus historical perspective

Directions to Hospitals Treating Dysplastic nevus

Risk calculators and risk factors for Dysplastic nevus historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Aditya Ganti M.B.B.S. [2]


Melanoma was first described by Hippocrates in the 5th century BC. It was often described as the fatal black tumor. In 1838, the term melanoma was first proposed by Sir Robert Carswell, a British pathologist. In 1956, Henry Lancaster, an Australian mathematician, was the first to discover the association between UV radiation exposure and development of melanoma. In 2003, BRAF mutations were first identified in the pathogenesis of melanoma.

Historical Perspective



  1. 1.0 1.1 Karamanou M, Liappas I, Stamboulis E, Lymperi M, Kyriakis K, Androutsos G (2012). "Sir Robert Carswell (1793-1857): coining the term "melanoma"". J BUON. 17 (2): 400–2. PMID 22740229.
  2. Urteaga O, Pack GT (1966). "On the antiquity of melanoma". Cancer. 19 (5): 607–10. PMID 5326247.
  3. Norris W. (1820). "Case of fungoid disease". Edinb Med Surg J. 16: 562–565.
  4. 4.0 4.1 4.2 4.3 Rebecca VW, Sondak VK, Smalley KS (2012). "A brief history of melanoma: from mummies to mutations". Melanoma Res. 22 (2): 114–22. doi:10.1097/CMR.0b013e328351fa4d. PMC 3303163. PMID 22395415.
  5. LANCASTER HO (1956). "Some geographical aspects of the mortality from melanoma in Europeans". Med J Aust. 43 (26): 1082–7. PMID 13347440.
  6. Michaloglou C, Vredeveld LC, Soengas MS, Denoyelle C, Kuilman T, van der Horst CM; et al. (2005). "BRAFE600-associated senescence-like cell cycle arrest of human naevi". Nature. 436 (7051): 720–4. doi:10.1038/nature03890. PMID 16079850.
  7. Breslow A, Macht SD (1977). "Optimal size of resection margin for thin cutaneous melanoma". Surg Gynecol Obstet. 145 (5): 691–2. PMID 910211.