Cytidylate cyclase

Jump to: navigation, search

In enzymology, a cytidylate cyclase (EC 4.6.1.6) is an enzyme that catalyzes the chemical reaction

CTP 3',5'-cyclic CMP + diphosphate

Hence, this enzyme has one substrate, CTP, and two products, 3',5'-cyclic CMP and diphosphate.

This enzyme belongs to the family of lyases, specifically the class of phosphorus-oxygen lyases. The systematic name of this enzyme class is CTP diphosphate-lyase (cyclizing; 3',5'-cyclic-CMP-forming). Other names in common use include 3',5'-cyclic-CMP synthase, cytidylyl cyclase, cytidyl cyclase, and CTP diphosphate-lyase (cyclizing).

References

  • IUBMB entry for 4.6.1.6
  • BRENDA references for 4.6.1.6 (Recommended.)
  • PubMed references for 4.6.1.6
  • PubMed Central references for 4.6.1.6
  • Google Scholar references for 4.6.1.6
  • Cech SY, Ignarro LJ (1978). "Cytidine 3',5'-monophosphate (cyclic CMP) formation by homogenates of mouse liver". Biochem. Biophys. Res. Commun. 80: 119&ndash, 25. PMID 23778.
  • JH (1985). "3',5'-Cyclic UMP, -cyclic IMP, -cyclic TMP and related enzymes in mammalian-tissues". Biochem. Soc. Trans. 13: 1134&ndash, 1135.

External links

The CAS registry number for this enzyme class is 65357-82-6.

Gene Ontology (GO) codes


Linked-in.jpg