Cysteine-conjugate transaminase

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In enzymology, a cysteine-conjugate transaminase (EC 2.6.1.75) is an enzyme that catalyzes the chemical reaction

S-(4-bromophenyl)-L-cysteine + 2-oxoglutarate S-(4-bromophenyl)mercaptopyruvate + L-glutamate

Thus, the two substrates of this enzyme are S-(4-bromophenyl)-L-cysteine and 2-oxoglutarate, whereas its two products are S-(4-bromophenyl)mercaptopyruvate and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is S-(4-bromophenyl)-L-cysteine:2-oxoglutarate aminotransferase. Other names in common use include cysteine conjugate aminotransferase, and cysteine-conjugate alpha-ketoglutarate transaminase (CAT-1).

References

  • IUBMB entry for 2.6.1.75
  • BRENDA references for 2.6.1.75 (Recommended.)
  • PubMed references for 2.6.1.75
  • PubMed Central references for 2.6.1.75
  • Google Scholar references for 2.6.1.75
  • Tateishi M (1988). "Purification and characterization of cysteine conjugate transaminases from rat liver". Xenobiotica. 18: 1015&ndash, 28. PMID 2852419.

External links

The CAS registry number for this enzyme class is 117698-05-2.

Gene Ontology (GO) codes


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