Columbamine O-methyltransferase

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In enzymology, a columbamine O-methyltransferase (EC 2.1.1.118) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + columbamine S-adenosyl-L-homocysteine + palmatine

Thus, the two substrates of this enzyme are S-adenosyl methionine and columbamine, whereas its two products are S-adenosylhomocysteine and palmatine.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:columbamine O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.

References

  • IUBMB entry for 2.1.1.118
  • BRENDA references for 2.1.1.118 (Recommended.)
  • PubMed references for 2.1.1.118
  • PubMed Central references for 2.1.1.118
  • Google Scholar references for 2.1.1.118
  • Rueffer M, Amann M, Zenk MH (1986). "S-Adenosyl-L-methionine:columbamine O-methyltransferase, a compartmentalized enzyme in protoberberine biosynthesis". Plant Cell Reports. 3: 182&ndash, 185.

External links

The CAS registry number for this enzyme class is 105843-76-3.

Gene Ontology (GO) codes


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