Codoxime

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Codoxime
Codoxime.svg
Clinical data
SynonymsCodoxime
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC20H24N2O5
Molar mass372.415 g/mol
3D model (JSmol)

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Overview

Codoxime is an opiate analogue that is an derivative of hydrocodone, where the 6-ketone group has been replaced by carboxymethyloxime. It has primarily antitussive effects[1] and was found to have moderate potential to cause dependence in animal studies.[2]


References

  1. Jack Fishman. Morphinone and Codeinone Derivatives. US Patent 3153042
  2. Jasinski DR, Martin WR. Assessment of the dependence-producing properties of dihydrocodeinone and codoxime. Clinical Pharmacology and Therapeutics. 1967 Mar-Apr;8(2):266-70. PMID 6021586





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