Cobamamide

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Cobamamide
Systematic (IUPAC) name
Coα-[α-(5,6-dimethylbenzimidazolyl)]-Coβ-
(5'-deoxy-5'-adenosyl)cobamide
Identifiers
CAS number 13870-90-1
ATC code B03BA04
PubChem 5459907
Chemical data
Formula C72H100CoN18O17P 
Mol. mass 1579.58 g/mol
Pharmacokinetic data
Bioavailability ?
Metabolism ?
Half life ?
Excretion ?
Therapeutic considerations
Pregnancy cat.

?

Legal status

OTC(US)

Routes ?

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Cobamamide (AdoCbl), which is also known as adenosylcobalamin and dibencozide, is, along with methylcobalamin (MeCbl), one of the active forms of vitamin B12. As a nutritional supplement, it is available in tabletted form, but unlike cyanocobalamin, methylcobalamin, and hydroxocobalamin, it is not available in injectable form.

An enzyme that uses adenosylcobalamin as a cofactor is methylmalonyl-CoA mutase (MCM).

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