Clostridium difficile infection prevention

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.

Overview

There are no vaccines available for the prevention of C. difficile infection. Individuals in healthcare settings may reduce the risk of C. difficile infection by washing hands using soap and water (alcohol-based products are not effective), minimizing unnecessary use of antibiotic administration, and properly isolating infected patients with adequate post-discharge room disinfection.

Prevention

There are no vaccines available for the prevention of C. difficile infection.[1] The following prevention strategies have demonstrated significant reduction in the rate of C. difficile infections[1]:

  • Use soap and water for hand wash in healthcare settings (alcohol-based products are not effective)
  • Minimize unnecessary antiobitic administration among hospitalized patients
  • Isolate hospitalized patients diagnosed with C. difficile infection
  • Disinfect hospital rooms post-discharge
  • Consider using probiotics to prevent C. difficile colonization (controversial with mixed results but may be helpful)

References

  1. 1.0 1.1 Leffler DA, Lamont JT (2015). "Clostridium difficile infection". N Engl J Med. 372 (16): 1539–48. doi:10.1056/NEJMra1403772. PMID 25875259.

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