Cerebral palsy MRI

Jump to: navigation, search

Cerebral palsy Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Cerebral Palsy from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Cerebral palsy MRI On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Cerebral palsy MRI

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Cerebral palsy MRI

CDC on Cerebral palsy MRI

Cerebral palsy MRI in the news

Blogs on Cerebral palsy MRI

Directions to Hospitals Treating Psoriasis

Risk calculators and risk factors for Cerebral palsy MRI

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Iqra Qamar M.D.[2]

Overview

MRI is the diagnostic neuroimaging study of choice especially for older children and is preferred over CT scan. The diagnostic yield of MRI depends upon the type of CP (mixed > quadriplegic > hemiplegic > diplegic > ataxic > dyskinetic) and the timing of birth. MRI findings in patients with CP may include hypoxic-ischemic lesions (eg, periventricular leukomalacia-PVL), cortical malformations and lesions of the basal ganglia.

MRI

  • MRI is the diagnostic neuroimaging study of choice especially for older children.[1][2][3][4][5]
  • MRI is preferred over CT due to
    • Higher diagnostic yield
    • Role in finding out the etiology and timing of insult
  • The diagnostic yield of MRI depends upon:
    • The type of CP (mixed > quadriplegic > hemiplegic > diplegic > ataxic > dyskinetic)
    • Timing of birth (scans are more often abnormal in preterm compared with term infants)
  • MRI findings in patients with CP include:
  • MRI may show:
  • MRI is found to be abnormal in 90% of children with cerebral palsy.[6]
  • MRI has an important role in predicting neurodevelopmental outcomes in preterm infants.[7]
  • MRI may be normal in cerebral palsy- does not exclude the diagnosis and require exclusion of metabolic and genetic etiologies
Hyperintense lesions of bilateral thalami Axial on T-1 MRI associated with hypoxic-ischemic encephelopathy- one of the most common causes of cerebral palsy in term neonates, source: Radiopedia.org

References

  1. Ashwal S, Russman BS, Blasco PA, Miller G, Sandler A, Shevell M, Stevenson R (2004). "Practice parameter: diagnostic assessment of the child with cerebral palsy: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society". Neurology. 62 (6): 851–63. PMID 15037681.
  2. Truwit CL, Barkovich AJ, Koch TK, Ferriero DM (1992). "Cerebral palsy: MR findings in 40 patients". AJNR Am J Neuroradiol. 13 (1): 67–78. PMID 1595496.
  3. Krägeloh-Mann I, Petersen D, Hagberg G, Vollmer B, Hagberg B, Michaelis R (1995). "Bilateral spastic cerebral palsy--MRI pathology and origin. Analysis from a representative series of 56 cases". Dev Med Child Neurol. 37 (5): 379–97. PMID 7768338.
  4. Miller G, Cala LA (1989). "Ataxic cerebral palsy--clinico-radiologic correlations". Neuropediatrics. 20 (2): 84–9. doi:10.1055/s-2008-1071271. PMID 2739880.
  5. "Bilateral lesions of thalamus and basal ganglia: origin and outcome - Krägeloh-Mann - 2007 - Developmental Medicine & Child Neurology - Wiley Online Library".
  6. Bax M, Tydeman C, Flodmark O (2006). "Clinical and MRI correlates of cerebral palsy: the European Cerebral Palsy Study". JAMA. 296 (13): 1602–8. doi:10.1001/jama.296.13.1602. PMID 17018805.
  7. Woodward LJ, Anderson PJ, Austin NC, Howard K, Inder TE (2006). "Neonatal MRI to predict neurodevelopmental outcomes in preterm infants". N. Engl. J. Med. 355 (7): 685–94. doi:10.1056/NEJMoa053792. PMID 16914704.

Linked-in.jpg