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E number{{#property:P628}}
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Molar mass257.713

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Centrophenoxine (also called Meclofenoxate, and formerly sold under the brand name Lucidril®) is a drug used to treat the symptoms of senile dementia and Alzheimer's Disease. It is a compound of two biochemicals: dimethylaminoethanol (DMAE) and parachlorophenoxyacetate (pCPA). DMAE is a natural substance, found especially in fish, and also produced in the human brain. pCPA is a synthetic compound that resembles to a variety of plant hormones called auxins.

Like DMAE, it is a precursor to the neurotransmitter acetylcholine and may increase levels of this chemical in the CNS. It is reported to improve memory and general cognition.

It is also used off-label as a nootropic, often combined with a racetam drug such as piracetam.

Side Effects & Contraindications

Possible side effects may include nausea or mild dizziness. People with severely high blood pressure or convulsive disorders such as epilepsy should avoid Centrophenoxine. [1] Large doses may cause tight jaw clenching.


1. Centrophenoxine Page @ The American Academy of Anti-Aging Medicine

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