Carcinoma

Jump to: navigation, search
Carcinoma
OMIM 8010/3
MeSH D002277

WikiDoc Resources for Carcinoma

Articles

Most recent articles on Carcinoma

Most cited articles on Carcinoma

Review articles on Carcinoma

Articles on Carcinoma in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Carcinoma

Images of Carcinoma

Photos of Carcinoma

Podcasts & MP3s on Carcinoma

Videos on Carcinoma

Evidence Based Medicine

Cochrane Collaboration on Carcinoma

Bandolier on Carcinoma

TRIP on Carcinoma

Clinical Trials

Ongoing Trials on Carcinoma at Clinical Trials.gov

Trial results on Carcinoma

Clinical Trials on Carcinoma at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Carcinoma

NICE Guidance on Carcinoma

NHS PRODIGY Guidance

FDA on Carcinoma

CDC on Carcinoma

Books

Books on Carcinoma

News

Carcinoma in the news

Be alerted to news on Carcinoma

News trends on Carcinoma

Commentary

Blogs on Carcinoma

Definitions

Definitions of Carcinoma

Patient Resources / Community

Patient resources on Carcinoma

Discussion groups on Carcinoma

Patient Handouts on Carcinoma

Directions to Hospitals Treating Carcinoma

Risk calculators and risk factors for Carcinoma

Healthcare Provider Resources

Symptoms of Carcinoma

Causes & Risk Factors for Carcinoma

Diagnostic studies for Carcinoma

Treatment of Carcinoma

Continuing Medical Education (CME)

CME Programs on Carcinoma

International

Carcinoma en Espanol

Carcinoma en Francais

Business

Carcinoma in the Marketplace

Patents on Carcinoma

Experimental / Informatics

List of terms related to Carcinoma

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

In medicine, carcinoma is any cancer that arises from epithelial cells. It is malignant by definition: carcinomas invade surrounding tissues and organs, and may spread to lymph nodes and distal sites (metastasis). Carcinoma in situ (CIS) is a pre-malignant condition, in which cytological signs of malignancy are present, but there is no histological evidence of invasion through the epithelial basement membrane.

Classification of carcinoma

Carcinoma, like all neoplasia, is classified by its histopathological appearance. Adenocarcinoma and squamous cell carcinoma, two common descriptive terms for tumours, reflect the fact that these cells may have glandular or squamous cell appearances respectively. Severely anaplastic tumours might be so undifferentiated that they do not have a distinct histological appearance (undifferentiated carcinoma).

Sometimes a tumour is referred to by the presumptive organ of the primary (eg carcinoma of the prostate) or the putative cell of origin (hepatocellular carcinoma, renal cell carcinoma).

Types of carcinoma by ICD-O Code

(8010-8790) Epithelial

Types of lung carcinoma

  • Adenocarcinoma is a malignant tumor originating in the epithelial cells of glandular tissue and forming glandular structures. This is common in the lung (forming 30-40% of all lung carcinomas). It is found peripherally, arising from goblet cells or type II pneumocytes.
  • Large cell undifferentiated carcinomas account for 10-15% of lung neoplasms. These are aggressive and difficult to recognise due to the undifferentiated nature. These are most commonly central in the lung.
  • Sinonasal undifferentiated carcinoma

Staging and grading

The staging of cancers is the extent of spread of the neoplasm. Grading is the system used to record the tumors degree of differentiation from the parent tissue. High grade shows little differentiation and the prognosis is therefore poor.

Carcinomas, like all cancers, are staged according to the extent of disease. The UICC/AJCC TNM system is often used, however for some common tumors, classic staging methods (such as the Dukes classification for colon cancer) are still used.

Related chapters

References


bg:Рак (болест) da:Carcinom de:Karzinom it:Carcinoma he:קרצינומה nl:Carcinoom sv:Carcinom



Linked-in.jpg