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Bolaamphiphiles (also known as bolaform surfactants, bolaphiles, or alpha-omega-type surfactants) are amphiphilic molecules that have hydrophilic groups at both ends of a sufficiently long hydrophobic hydrocarbon chain. Compared to single- headed amphiphiles, the introduction of a second head- group generally induces a higher solubility in water, an increase in the critical micelle concentration (cmc), and a decrease in aggregation number. The aggregate morphologies of bolaamphiphiles include spheres, cylinders, disks, and vesicles.