Big dynorphin

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Big dynorphin is a form of dynorphin consisting of dynorphin A and dynorphin B.[1]

It binds to the kappa-opioid receptor.[2]

References

  1. Tan-No K, Esashi A, Nakagawasai O; et al. (2002). "Intrathecally administered big dynorphin, a prodynorphin-derived peptide, produces nociceptive behavior through an N-methyl-D-aspartate receptor mechanism". Brain Res. 952 (1): 7–14. PMID 12363399.
  2. Merg F, Filliol D, Usynin I; et al. (2006). "Big dynorphin as a putative endogenous ligand for the kappa-opioid receptor". J. Neurochem. 97 (1): 292–301. doi:10.1111/j.1471-4159.2006.03732.x. PMID 16515546.

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