Aspergillus nidulans

Jump to: navigation, search

Aspergillosis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Aspergillosis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Chest X Ray

CT

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Future or Investigational Therapies

Case Studies

Case #1

Aspergillus nidulans On the Web

Most recent articles

cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Aspergillus nidulans

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Aspergillus nidulans

CDC on Aspergillus nidulans

Aspergillus nidulans in the news

Blogs on Aspergillus nidulans

Aspergillosis

Risk calculators and risk factors for Aspergillus nidulans

Aspergillus nidulans
Scientific classification
Kingdom: Fungi
Phylum: Ascomycota
Class: Eurotiomycetes
Order: Eurotiales
Family: Trichocomaceae
Genus: Aspergillus
Species: A. nidulans
Binomial name
Aspergillus nidulans
G Winter 1884
Synonyms

Emericella nidulans

Aspergillus nidulans (also called Emericella nidulans) is one of many species of filamentous fungi in the phylum Ascomycota. It has been an important research organism for studying eukaryotic cell biology [1] for over 50 years, [2] being used to study a wide range of subjects including recombination, DNA repair, mutation, cell cycle control, pathogenesis, and metabolism.[3] It is one of the few species in its genus able to form sexual spores through meiosis, allowing crossing of strains in the laboratory. A. nidulans is a homothallic fungus, meaning it is able to self-fertilize and form fruiting bodies in the absence of a mating partner.

Genome

The genome of A. nidulans, sequenced at the Broad Institute, was published in December 2005. [4] It is 30 million base pairs in size and is predicted to contain around 9,500 protein-coding genes on eight chromosomes.

References

  1. Osmani SA, Mirabito PM (2004). "The early impact of genetics on our understanding of cell cycle regulation in Aspergillus nidulans". Fungal Genet Biol. 41 (4): 401–10. PMID 14998523.
  2. Martinelli, S. D. (1994). Aspergillus: 50 years on. Elsevier. ISBN 0-444-81762-X. Unknown parameter |coauthors= ignored (help)
  3. Nierman WC, May G, Kim HS, Anderson MJ, Chen D, Denning DW (2005). "What the Aspergillus genomes have told us". Med Mycol. 43 Suppl 1: S3–5. PMID 16110785.
  4. Galagan JE; et al. (2005). "Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae". Nature. 438 (7071): 1105–15. PMID 16372000.

External links

Template:Ascomycetes-stub


Linked-in.jpg