Amine sulfotransferase

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In enzymology, an amine sulfotransferase (EC 2.8.2.3) is an enzyme that catalyzes the chemical reaction

3'-phosphoadenylyl sulfate + an amine adenosine 3',5'-bisphosphate + a sulfamate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and amine, whereas its two products are adenosine 3',5'-bisphosphate and sulfamate.

This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:amine N-sulfotransferase. Other names in common use include arylamine sulfotransferase, and amine N-sulfotransferase. This enzyme participates in sulfur metabolism.

References

  • IUBMB entry for 2.8.2.3
  • BRENDA references for 2.8.2.3 (Recommended.)
  • PubMed references for 2.8.2.3
  • PubMed Central references for 2.8.2.3
  • Google Scholar references for 2.8.2.3
  • Ramaswamy SG, Jakoby WB (1987). "Amine N-sulfotransferase". J. Biol. Chem. 262: 10039&ndash, 43. PMID 3475273.
  • Roy, AB (1960). "The enzymic synthesis of aryl sulphamates". Biochem. J. 74: 49&ndash, 56.

External links

The CAS registry number for this enzyme class is 9026-08-8.

Gene Ontology (GO) codes


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