Podophyllum peltatum

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Mayapple
Scientific classification
Kingdom: Plantae
Division: Magnoliophyta
Class: Magnoliopsida
Order: Ranunculales
Family: Berberidaceae
Genus: Podophyllum
Species: P. peltatum
Binomial name
Podophyllum peltatum
L.
A flowering plant
Fruit touching the earth on June 14, 2007
Fruit on July 18, 2007

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Overview

Podophyllum peltatum [1] (the mayapple) is a herbaceous perennial plant in the family Berberidaceae, native to the eastern part of North America.

The stems grow to 30-40 cm tall, with palmately lobed leaves up to 20-30 cm diameter with 5-9 deeply cut lobes. The plant produces two growth forms. The ones with a single umbrella-like leaf do not produce any flower or fruit. The plants having a twin leaf (rarely three-leaf) structure, however, bear a single white flower 3-5 cm diameter with six (rarely up to nine) petals, between the two leaves; this matures into a yellow-greenish fruit 2-5 cm long. The plant appears in colonies in open woodlands. Individual shoots are often connected by systems of thick tubers and rhizomes. [2]

Despite the common name mayapple [3], it is the flower that appears in early May, not the "apple", which appears later during the summer. The Mayapple is also called the Devil's apple, Hogapple, Indian apple, Umbrella plant (shape of the leaves), Wild lemon (flavor of the fruit), Wild mandrake, and American mandrake (shape of rhizomes).

According to Brian Fondren, the rhizome of the mayapple has been used for a variety of medicinal purposes, originally by Native Americans and later by other settlers. [2]

Toxicity

All the parts of the plant, excepting the fruit, are poisonous. This plant can kill humans within 24 hours. Even the fruit, though not dangerously poisonous, can cause unpleasant red/yellow diarrhea. The plant contains podophyllotoxin [4], which is used as a cytostatic and topically in the treatment of genital warts.

Notes

  1. TSN 18850. Integrated Taxonomic Information System.
  2. 2.0 2.1 Fondren, Brian T. "Mayapple". Ethnobotanical leaflets. Retrieved 2006-06-03. 
  3. Podophyllum peltatum at USDA PLANTS Database
  4. Moraes, R.M., H. Lata, E. Bedir, M. Maqbool, and K. Cushman. 2002. On American Mayapple as practical source of podophyllotoxin p. 527–532. In: J. Janick and A. Whipkey (eds.), Trends in new crops and new uses. ASHS Press, Alexandria, VA.

References

External links


Cost Effectiveness of Podophyllum peltatum

| group5 = Clinical Trials Involving Podophyllum peltatum | list5 = Ongoing Trials on Podophyllum peltatum at Clinical Trials.govTrial results on Podophyllum peltatumClinical Trials on Podophyllum peltatum at Google


| group6 = Guidelines / Policies / Government Resources (FDA/CDC) Regarding Podophyllum peltatum | list6 = US National Guidelines Clearinghouse on Podophyllum peltatumNICE Guidance on Podophyllum peltatumNHS PRODIGY GuidanceFDA on Podophyllum peltatumCDC on Podophyllum peltatum


| group7 = Textbook Information on Podophyllum peltatum | list7 = Books and Textbook Information on Podophyllum peltatum


| group8 = Pharmacology Resources on Podophyllum peltatum | list8 = AND (Dose)}} Dosing of Podophyllum peltatumAND (drug interactions)}} Drug interactions with Podophyllum peltatumAND (side effects)}} Side effects of Podophyllum peltatumAND (Allergy)}} Allergic reactions to Podophyllum peltatumAND (overdose)}} Overdose information on Podophyllum peltatumAND (carcinogenicity)}} Carcinogenicity information on Podophyllum peltatumAND (pregnancy)}} Podophyllum peltatum in pregnancyAND (pharmacokinetics)}} Pharmacokinetics of Podophyllum peltatum


| group9 = Genetics, Pharmacogenomics, and Proteinomics of Podophyllum peltatum | list9 = AND (pharmacogenomics)}} Genetics of Podophyllum peltatumAND (pharmacogenomics)}} Pharmacogenomics of Podophyllum peltatumAND (proteomics)}} Proteomics of Podophyllum peltatum


| group10 = Newstories on Podophyllum peltatum | list10 = Podophyllum peltatum in the newsBe alerted to news on Podophyllum peltatumNews trends on Podophyllum peltatum


| group11 = Commentary on Podophyllum peltatum | list11 = Blogs on Podophyllum peltatum

| group12 = Patient Resources on Podophyllum peltatum | list12 = Patient resources on Podophyllum peltatumDiscussion groups on Podophyllum peltatumPatient Handouts on Podophyllum peltatumDirections to Hospitals Treating Podophyllum peltatumRisk calculators and risk factors for Podophyllum peltatum


| group13 = Healthcare Provider Resources on Podophyllum peltatum | list13 = Symptoms of Podophyllum peltatumCauses & Risk Factors for Podophyllum peltatumDiagnostic studies for Podophyllum peltatumTreatment of Podophyllum peltatum

| group14 = Continuing Medical Education (CME) Programs on Podophyllum peltatum | list14 = CME Programs on Podophyllum peltatum

| group15 = International Resources on Podophyllum peltatum | list15 = Podophyllum peltatum en EspanolPodophyllum peltatum en Francais

| group16 = Business Resources on Podophyllum peltatum | list16 = Podophyllum peltatum in the MarketplacePatents on Podophyllum peltatum

| group17 = Informatics Resources on Podophyllum peltatum | list17 = List of terms related to Podophyllum peltatum


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