Alstrom syndrome surgery

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Alstrom syndrome Microchapters

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Patient Information

Overview

Historical Perspective

Pathophysiology

Differentiating Alstrom syndrome from other Diseases

Epidemiology and Demographics

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

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CT

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Treatment

Medical Therapy

Surgery

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Tertiary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

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Case #1

Alstrom syndrome surgery On the Web

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Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Alstrom syndrome surgery

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Alstrom syndrome surgery in the news

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Directions to Hospitals Treating Alstrom syndrome

Risk calculators and risk factors for Alstrom syndrome surgery

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]; Raviteja Guddeti, M.B.B.S. [3]

Surgery

Sensorineural Hearing Loss

Myringotomy has been helpful in individuals with recurrent otitis media (‘glue ear’). Hearing can be maximized with bilateral digital hearing aids. Cochlear implantation has benefited some patients.

Cardiomyopathy

Cardiac transplantation has been successful in isolated cases.

Urological Disorders

Urinary diversion or self-catheterization to manage voiding difficulties are required in some individuals.

Renal Failure

Renal transplantation is indicated in patients with ESRD refractory to medical therapy. But it can be contraindicated in the presence of other complications including morbid obesity, uncontrolled diabetes, and cardiomyopathy.

Liver Dysfunction

Patients who fail to respond to medication and banding are candidates for a transjugular intrahepatic portosystemic shunt (TIPS) to decrease risk of variceal bleeding caused by portal hypertension. Patients with significant portal hypertension should be evaluated early for liver transplantation.

References


Cardiology


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