Jump to: navigation, search

In enzymology, an alpha,alpha-phosphotrehalase (EC is an enzyme that catalyzes the chemical reaction

alpha,alpha-trehalose 6-phosphate + H2O D-glucose + D-glucose 6-phosphate

Thus, the two substrates of this enzyme are alpha,alpha'-trehalose 6-phosphate and H2O, whereas its two products are D-glucose and D-glucose 6-phosphate.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is alpha,alpha-trehalose-6-phosphate phosphoglucohydrolase. This enzyme is also called phosphotrehalase. This enzyme participates in starch and sucrose metabolism.


  • IUBMB entry for
  • BRENDA references for (Recommended.)
  • PubMed references for
  • PubMed Central references for
  • Google Scholar references for
  • Bhumiratana A, Anderson RL, Costilow RN (1974). "Trehalose metabolism by Bacillus popilliae". J. Bacteriol. 119: 484&ndash, 93. PMID 4369400.

External links

The CAS registry number for this enzyme class is 54576-93-1.

Gene Ontology (GO) codes