Adult-onset Still's disease physical examination

Jump to: navigation, search

Adult-onset Still's disease

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Adult-onset Still’s Disease from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Template:Adult-onset Still's disease On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Template:Adult-onset Still's disease

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Adult-onset Still's disease physical examination

CDC on Template:Adult-onset Still's disease

Template:Adult-onset Still's disease in the news

Blogs on Template:Adult-onset Still's disease

Risk calculators and risk factors for Template:Adult-onset Still's disease

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]

Overview

On physical examination, a patient suffering from adult-onset Still's disease (AOSD) may appear fatigued, has a high grade fever (spiking fever), tachycardia, salmon colored maculopapular rash on trunk and/or extremities, lymphadenopathy, hepatosplenomegaly, pleural and pericardial friction rub (due to underlying pleuritis and pericarditis).

Physical Examination

On physical examination, the following findings may be observed:[1][2][3][4]

Appearance of the patient

Vital signs

Skin

HEENT

  • Within normal limits

Neck

Lungs

Heart

Abdomen

References

  1. Yamaguchi M, Ohta A, Tsunematsu T, Kasukawa R, Mizushima Y, Kashiwagi H, Kashiwazaki S, Tanimoto K, Matsumoto Y, Ota T (March 1992). "Preliminary criteria for classification of adult Still's disease". J. Rheumatol. 19 (3): 424–30. PMID 1578458.
  2. Kastner DL, Aksentijevich I, Goldbach-Mansky R (March 2010). "Autoinflammatory disease reloaded: a clinical perspective". Cell. 140 (6): 784–90. doi:10.1016/j.cell.2010.03.002. PMC 3541025. PMID 20303869.
  3. Oba Y, Abu-Salah T (2012). "The prevalence and diagnostic significance of eosinophilic pleural effusions: a meta-analysis and systematic review". Respiration. 83 (3): 198–208. doi:10.1159/000327200. PMID 21576924.
  4. Antoniou KM, Margaritopoulos GA, Giannarakis I, Choulaki C, Fountoulakis N, Siafakas NM, Sidiropoulos P (2013). "Adult Onset Still's Disease: A Case Report with a Rare Clinical Manifestation and Pathophysiological Correlations". Case Rep Med. 2013: 981232. doi:10.1155/2013/981232. PMC 3568868. PMID 23424598.
  5. Feuerstein JL, Klein DE, Mikhitarian MA, Mehta A (May 2017). "Quotidian High Spiking Fevers in Adult Still's Disease". Am J Case Rep. 18: 580–588. PMC 5453396. PMID 28546530.
  6. Sunderkötter C, Frieling U, Nashan D, Metze D (December 1998). "[Adult-onset Still's disease and its characteristic rash]". Hautarzt (in German). 49 (12): 920–4. PMID 9914890.
  7. Jeon YK, Paik JH, Park SS, Park SO, Kim YA, Kim JE, Song YW, Kim CW (October 2004). "Spectrum of lymph node pathology in adult onset Still's disease; analysis of 12 patients with one follow up biopsy". J. Clin. Pathol. 57 (10): 1052–6. doi:10.1136/jcp.2004.018010. PMC 1770453. PMID 15452159.
  8. Quartuccio L, Salvin S, Zuliani F, Mansutti E, De Vita S (2012). "Pleuritis is a red flag for adult-onset Still's disease which may require biologic therapies". Clin. Exp. Rheumatol. 30 (5): 807. PMID 22992345.
  9. Masson C, Le Loët X, Lioté F, Renou P, Dubost JJ, Boissier MC, Brithmer L, Brégeon C, Audran M (December 1995). "Adult Still's disease: part I. Manifestations and complications in sixty-five cases in France". Rev Rhum Engl Ed. 62 (11): 748–57. PMID 8869216.
  10. Andrès E, Kurtz JE, Perrin AE, Pflumio F, Ruellan A, Goichot B, Dufour P, Blicklé JF, Brogard JM, Schlienger JL (2003). "Retrospective monocentric study of 17 patients with adult Still's disease, with special focus on liver abnormalities". Hepatogastroenterology. 50 (49): 192–5. PMID 12630021.

Linked-in.jpg