Adult-onset Still's disease history and symptoms

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Adult-onset Still's disease

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]

Overview

Obtaining a comprehensive history is an integral part of diagnosing adult-onset Still's disease (AOSD). The typical age of onset of adult-onset Still's disease (AOSD) is between 16 to 35 years of age. A patient suffering from AOSD may present with a fever greater than equal to 39 degrees celcius (102.2 degrees Fahrenheit) for greater than equal to 1 week along with associated arthralgia/arthritis for greater than equal to 2 weeks. There may be a maculopapular non-pruritic rash on the trunk or limbs. Patients may also complain of sore throat and lymphadenopathy. The symptoms of AOSD evolve over a period of weeks.

History

Obtaining a comprehensive history is an integral part of diagnosing adult-onset Still's disease (AOSD). The following findings on history may help identify AOSD:[1]

Age of onset

  • The typical age of onset of adult-onset Still's disease (AOSD) is between 16 to 35 years of age.

Family history

Initial presentation

Past medical history

  • The symptoms of AOSD evolve over a period of weeks.

Symptoms

Common symptoms

The common symptoms of AOSD include the following:[2][3]

Less common symptoms

Less common symptoms of AOSD include the following:[4]

References

  1. Wouters JM, van de Putte LB (November 1986). "Adult-onset Still's disease; clinical and laboratory features, treatment and progress of 45 cases". Q. J. Med. 61 (235): 1055–65. PMID 3659248.
  2. Efthimiou P, Paik PK, Bielory L (May 2006). "Diagnosis and management of adult onset Still's disease". Ann. Rheum. Dis. 65 (5): 564–72. doi:10.1136/ard.2005.042143. PMC 1798146. PMID 16219707.
  3. Wouters JM, van de Putte LB (November 1986). "Adult-onset Still's disease; clinical and laboratory features, treatment and progress of 45 cases". Q. J. Med. 61 (235): 1055–65. PMID 3659248.
  4. Masson C, Le Loët X, Lioté F, Renou P, Dubost JJ, Boissier MC, Brithmer L, Brégeon C, Audran M (December 1995). "Adult Still's disease: part I. Manifestations and complications in sixty-five cases in France". Rev Rhum Engl Ed. 62 (11): 748–57. PMID 8869216.

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