Adult-onset Still's disease epidemiology and demographics

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Adult-onset Still's disease

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]

Overview

There is a dearth of data regarding the incidence and prevalence of adult-onset Still's disease (AOSD). In the Japanese and the European populations, the reported prevalence rates range from 10 to 340 cases per 100,000 individuals. The disease occurs worldwide and usually affects young adults (age 16-35 years). Adult-onset Still's disease (AOSD) affects females more than males. Aging adults affected by adult-onset Still's disease (AOSD) have a higher rate of development of complications related to AOSD and a higher mortality rate compared to younger individuals.

Epidemiology and Demographics

Incidence and prevalence

  • There is a dearth of data regarding the incidence and prevalence of adult-onset Still's disease (AOSD).
  • In the Japanese and the European populations, the reported prevalence rates range from 10 to 340 cases per 100,000 individuals.[1]
  • The disease occurs worldwide and usually affects young adults (age 16-35 years).
  • In France, the annual incidence of AOSD was estimated to be 0.16 per 100,000 individuals.[2]
  • In Japan, the annual incidence of AOSD was estimated to be 0.22 per 100,000 individuals.[3]
  • In Norway, the annual incidence of AOSD was estimated to be 0.4 per 100,000 individuals.[4]

Age

  • Aging adults affected by adult-onset Still's disease (AOSD) have a higher rate of development of complications related to AOSD and a higher mortality rate compared to younger individuals.[5]

Gender

  • Adult-onset Still's disease (AOSD) affects females more than males.[6][7]

Race

  • Adult-onset Still's disease (AOSD) affects Caucasians more than other races.[8]

References

  1. "Adult-onset Still's disease - ScienceDirect".
  2. Magadur-Joly G, Billaud E, Barrier JH, Pennec YL, Masson C, Renou P, Prost A (July 1995). "Epidemiology of adult Still's disease: estimate of the incidence by a retrospective study in west France". Ann. Rheum. Dis. 54 (7): 587–90. PMC 1009940. PMID 7668903.
  3. Wakai K, Ohta A, Tamakoshi A, Ohno Y, Kawamura T, Aoki R, Kojima M, Lin Y, Hashimoto S, Inaba Y, Minowa M, Aizawa S, Ichikawa Y, Miyasaka N (December 1997). "Estimated prevalence and incidence of adult Still's disease: findings by a nationwide epidemiological survey in Japan". J Epidemiol. 7 (4): 221–5. PMID 9465547.
  4. Evensen KJ, Nossent HC (2006). "Epidemiology and outcome of adult-onset Still's disease in Northern Norway". Scand. J. Rheumatol. 35 (1): 48–51. doi:10.1080/03009740510026616. PMID 16467042.
  5. "Epidemiology of Hospitalized Adult Onset Still's Disease in United States - ACR Meeting Abstracts".
  6. "Epidemiology of Hospitalized Adult Onset Still's Disease in United States - ACR Meeting Abstracts".
  7. "A controlled study of the long-term prognosis of adult still's disease - ScienceDirect".
  8. "Epidemiology of Hospitalized Adult Onset Still's Disease in United States - ACR Meeting Abstracts".

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