Acoustic neuroma differential diagnosis

Jump to: navigation, search

Acoustic neuroma Microchapters


Patient Information


Historical Perspective




Differentiating Acoustic neuroma from other Diseases

Epidemiology and Demographics

Risk Factors


Natural History, Complications and Prognosis



History and Symptoms

Physical Examination

Laboratory Findings


Chest X Ray



Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies


Medical Therapy


Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Acoustic neuroma differential diagnosis On the Web

Most recent articles

cited articles

Review articles

CME Programs

Powerpoint slides


American Roentgen Ray Society Images of Acoustic neuroma differential diagnosis

All Images
Echo & Ultrasound
CT Images

Ongoing Trials at Clinical

US National Guidelines Clearinghouse

NICE Guidance

FDA on Acoustic neuroma differential diagnosis

CDC on Acoustic neuroma differential diagnosis

Acoustic neuroma differential diagnosis in the news

Blogs on Acoustic neuroma differential diagnosis</small>

Directions to Hospitals Treating Acoustic neuroma

Risk calculators and risk factors for Acoustic neuroma differential diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]


Acoustic neuroma must be differentiated from meningioma, intracranial epidermoid cyst, facial nerve schwannoma, trigeminal schwannoma, ependymoma, leiomyoma, intranodal palisaded myofibroblastoma, malignant peripheral nerve sheath tumour (MPNST), gastrointestinal stromal tumor, neurofibroma, Meniere's disease, and Bell's palsy.[1]

Differential Diagnosis

Acoustic neuroma must be differentiated from:[2]

Differentiating features of common differential diagnosis are:[1]

Disease/Condition Differentiating Signs/Symptoms Findings on CT or MRI
  • Hearing loss is less common
  • Usually more homogeneous in appearance: significant signal heterogeneity with cystic or haemorrhagic areas is more typical of vestibular schwannoma than meningiomas (although cystic meningiomas do occur)
  • Meningiomas tend to have a broad dural base
  • Usually lack trumpet IAM sign
  • Calcification is more common
Intracranial epidermoid cyst
  • Hearing loss is less common
  • No enhancing component
  • Very high signal on DWI (Diffusion weighted imaging)
  • Does not widen the IAC (Internal auditory canal)
Facial nerve schwannoma
  • Facial weakness is common and occurs early
  • Sometimes associated with neurofibromatosis
  • CT and MRI imaging results are similar to acoustic neuroma but enhancement extends into the geniculate ganglion of the facial nerve and facial canal
Trigeminal schwannoma
  • Clinically associated with facial numbness
  • Hearing loss is less common
  • CT and MRI imaging displays a dumbbell-shaped mass over the petrous apex affecting Meckel cave.
  • The trigeminal nerve enhancement extends proximal to the tumor and does not extend into the IAM (internal acoustic meatus)


  1. 1.0 1.1 Acoustic Schwannoma. Radiopedia(2015) Accessed on October 2 2015
  2. Schwannoma. Librepathology(2015) Accessed on October 2 2015
  3. Chan PT, Tripathi S, Low SE, Robinson LQ (2007). "Case report--ancient schwannoma of the scrotum.". BMC Urol. 7: 1. PMC 1783662Freely accessible. PMID 17244372. doi:10.1186/1471-2490-7-1.