Acetarsol

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Acetarsol
Acetarsol.png
Systematic name (3-Acetamido-4-hydroxyphenyl)arsonic acid[1]
Other names 3-Acetamido-4-hydroxyphenylarsonic acidTemplate:Citation needed
Identifiers
CAS number 97-44-9
PubChem 1985
EINECS number 202-582-3
KEGG D07110
MeSH Acetarsol
ATC code A07AX02,G01AB01, P01CD02, P51AD05
SMILES CC(=O)Nc1cc(ccc1O)[As](O)(O)=O
InChI InChI=1/C8H10AsNO5/c1-5(11)10-7-4-6(9(13,14)15)2-3-8(7)12/h2-4,12H,1H3,(H,10,11)(H2,13,14,15)
Properties
Molecular formula C8AsNH10O5
Molar mass 275.0903 g mol−1
Hazards
EU classification Template:Hazchem T Dangerous for the Environment (Nature) N
R-phrases R23/25, R50/53
S-phrases S20/21, S28, S45, S60, S61
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Acetarsol is an anti-infective.[2] It was first discovered in 1921 at Pasteur Institute by Ernest Fourneau, and sold under the brand name Stovarsol (fourneau is the French word for stove).[3][4]

It has been given in suppositories.[5]

References

  1. "acetarsol - PubChem Public Chemical Database". The PubChem Project. USA: National Center for Biotechnology Information. 
  2. Chen MY, Smith NA, Fox EF, Bingham JS, Barlow D (April 1999). "Acetarsol pessaries in the treatment of metronidazole resistant Trichomonas vaginalis". Int J STD AIDS. 10 (4): 277–80. PMID 12035784. doi:10.1258/0956462991913943. 
  3. Éric Fouassier, Ces poisons qui guérissent, oct. 1996, p. 5.
  4. Traité de chimie organique, sous la direction de Victor Grignard, Paul Baud, vol. 22, Masson, 1959, p. 1127-1130.
  5. Gionchetti P, Rizzello F, Morselli C, Campieri M (October 2004). "Review article: problematic proctitis and distal colitis". Aliment. Pharmacol. Ther. 20 Suppl 4: 93–6. PMID 15352902. doi:10.1111/j.1365-2036.2004.02049.x. 

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