ARHGEF3

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Rho guanine nucleotide exchange factor (GEF) 3, also known as ARHGEF3, is a human gene.[1]

Function

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. This protein is similar to the NET1A protein.[1]

Interactions

ARHGEF3 has been shown to interact with RHOA[2] and RHOB.[2]

References

  1. 1.0 1.1 "Entrez Gene: ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3".
  2. 2.0 2.1 Arthur WT, Ellerbroek SM, Der CJ, Burridge K, Wennerberg K (Nov 2002). "XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC". J. Biol. Chem. 277 (45): 42964–72. doi:10.1074/jbc.M207401200. PMID 12221096.

External links

Further reading



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