ARD1A

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ARD1 homolog A, N-acetyltransferase (S. cerevisiae)
Identifiers
Symbols ARD1A ; ARD1; DXS707; MGC71248; TE2
External IDs OMIM: 300013 MGI1915255 HomoloGene2608
RNA expression pattern
PBB GE ARD1A 203025 at tn.png
More reference expression data
Orthologs

| | bgcolor="#C3FDB8" | Human | bgcolor="#C3FDB8" | Mouse |-

    | bgcolor="#C3FDB8" | Entrez 
    | bgcolor="#eeeeee" style="border-top:2px solid #dddddd; border-right:2px solid #dddddd"| 8260
    | bgcolor="#eeeeee" style="border-top:2px solid #dddddd; border-right:2px solid #dddddd"| 56292

|-

     | bgcolor="#C3FDB8" | Ensembl
     | bgcolor="#eeeeee" style="border-top:2px solid #dddddd; border-right:2px solid #dddddd"| ENSG00000102030
     | bgcolor="#eeeeee" style="border-top:2px solid #dddddd; border-right:2px solid #dddddd"| ENSMUSG00000031388

|-

    | bgcolor="#C3FDB8" | Uniprot
    | bgcolor="#eeeeee" style="border-top:2px solid #dddddd; border-right:2px solid #dddddd"| P41227
    | bgcolor="#eeeeee" style="border-top:2px solid #dddddd; border-right:2px solid #dddddd"| Q540H0

|-

    | bgcolor="#C3FDB8" | Refseq
    | bgcolor="#eeeeee" style="border-top:2px solid #dddddd; border-right:2px solid #dddddd" | NM_003491 (mRNA)
NP_003482 (protein)
| bgcolor="#eeeeee" style="border-top:2px solid #dddddd; border-right:2px solid #dddddd" |NM_019870 (mRNA)
NP_063923 (protein)

|-

    | bgcolor="#C3FDB8" | Location
    | bgcolor="#eeeeee" style="border-top:2px solid #dddddd; border-right:2px solid #dddddd"|  Chr X: 152.85 - 152.85 Mb 
    | bgcolor="#eeeeee" style="border-top:2px solid #dddddd; border-right:2px solid #dddddd"|  Chr X: 70.17 -  70.17 Mb 

|-

|-

    | bgcolor="#C3FDB8" | Pubmed search 
    | bgcolor="#eeeeee" style="border-top:2px solid #dddddd; border-right:2px solid #dddddd"| [1]
| bgcolor="#eeeeee" style="border-top:2px solid #dddddd; border-right:2px solid #dddddd"| [2]
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

ARD1 homolog A, N-acetyltransferase (S. cerevisiae), also known as ARD1A, is a human gene.[1]


References

  1. "Entrez Gene: ARD1A ARD1 homolog A, N-acetyltransferase (S. cerevisiae)".

Further reading

  • Tribioli C, Mancini M, Plassart E; et al. (1995). "Isolation of new genes in distal Xq28: transcriptional map and identification of a human homologue of the ARD1 N-acetyl transferase of Saccharomyces cerevisiae". Hum. Mol. Genet. 3 (7): 1061–7. PMID 7981673.
  • Brenner V, Nyakatura G, Rosenthal A, Platzer M (1997). "Genomic organization of two novel genes on human Xq28: compact head to head arrangement of IDH gamma and TRAP delta is conserved in rat and mouse". Genomics. 44 (1): 8–14. doi:10.1006/geno.1997.4822. PMID 9286695.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. PMID 11076863.
  • Simpson JC, Wellenreuther R, Poustka A; et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMID 11256614.
  • Jeong JW, Bae MK, Ahn MY; et al. (2003). "Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation". Cell. 111 (5): 709–20. PMID 12464182.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Sugiura N, Adams SM, Corriveau RA (2003). "An evolutionarily conserved N-terminal acetyltransferase complex associated with neuronal development". J. Biol. Chem. 278 (41): 40113–20. doi:10.1074/jbc.M301218200. PMID 12888564.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Wiemann S, Arlt D, Huber W; et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336.
  • Arnesen T, Anderson D, Baldersheim C; et al. (2005). "Identification and characterization of the human ARD1-NATH protein acetyltransferase complex". Biochem. J. 386 (Pt 3): 433–43. doi:10.1042/BJ20041071. PMID 15496142.
  • Asaumi M, Iijima K, Sumioka A; et al. (2005). "Interaction of N-terminal acetyltransferase with the cytoplasmic domain of beta-amyloid precursor protein and its effect on A beta secretion". J. Biochem. 137 (2): 147–55. doi:10.1093/jb/mvi014. PMID 15749829.
  • Fisher TS, Etages SD, Hayes L; et al. (2005). "Analysis of ARD1 function in hypoxia response using retroviral RNA interference". J. Biol. Chem. 280 (18): 17749–57. doi:10.1074/jbc.M412055200. PMID 15755738.
  • Bilton R, Mazure N, Trottier E; et al. (2005). "Arrest-defective-1 protein, an acetyltransferase, does not alter stability of hypoxia-inducible factor (HIF)-1alpha and is not induced by hypoxia or HIF". J. Biol. Chem. 280 (35): 31132–40. doi:10.1074/jbc.M504482200. PMID 15994306.
  • Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
  • Arnesen T, Gromyko D, Horvli O; et al. (2006). "Expression of N-acetyl transferase human and human Arrest defective 1 proteins in thyroid neoplasms". Thyroid. 15 (10): 1131–6. doi:10.1089/thy.2005.15.1131. PMID 16279846.
  • Arnesen T, Kong X, Evjenth R; et al. (2006). "Interaction between HIF-1 alpha (ODD) and hARD1 does not induce acetylation and destabilization of HIF-1 alpha". FEBS Lett. 579 (28): 6428–32. doi:10.1016/j.febslet.2005.10.036. PMID 16288748.
  • Kim SH, Park JA, Kim JH; et al. (2006). "Characterization of ARD1 variants in mammalian cells". Biochem. Biophys. Res. Commun. 340 (2): 422–7. doi:10.1016/j.bbrc.2005.12.018. PMID 16376303.
  • Mehrle A, Rosenfelder H, Schupp I; et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901.
  • Arnesen T, Gromyko D, Pendino F; et al. (2006). "Induction of apoptosis in human cells by RNAi-mediated knockdown of hARD1 and NATH, components of the protein N-alpha-acetyltransferase complex". Oncogene. 25 (31): 4350–60. doi:10.1038/sj.onc.1209469. PMID 16518407.
  • Beausoleil SA, Villén J, Gerber SA; et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.

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