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E number{{#property:P628}}
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Chemical and physical data
Molar mass273.36 g/mol
3D model (JSmol)

4-Acetoxy-DET (4-Acetoxy-N,N-diethyltryptamine), also known as ethacetin, ethylacybin or 4-AcO-DET is a hallucinogenic tryptamine. It was first synthesized in 1958 by Albert Hofmann in the Sandoz lab.[1]

Within the body a percentage may be partially hydrolized into the free phenol 4-HO-DET. Human studies concerning the metabolic fate of this drug are lacking.


4-Acetoxy-DET is orally active, and dosages of 10-25 mg are common. Effects last 4-6 hours.[2] The free base is also active when smoked in a dose range of 5-20 mg.[1] Smoking 4-acetoxy-DET greatly speeds up the onset; peak effects are experienced within 10 minutes, and are usually over within 1 hour.Template:Specify


4-Acetoxy-DET is unscheduled in the United States, but possession and sales of 4-Acetoxy-DET could be prosecuted under the Federal Analog Act because of its structural similarities to DET.


  1. 1.0 1.1 Erowid 4-Acetoxy-DET Vaults : Primer. Accessed on April 19, 2007.
  2. Tikhal: The Chemistry Continues by Alexander and Ann Shulgin. #16. 4-HO-DET. Accessed on April 19, 2007.

External links